Naomi Campbell, 49, goes TOPLESS for a selfie in bed

And returning back to her hotel, Naomi Campbell stripped off the baggy set, posing topless for her 8.4 million fans.  The 49-year-old beauty relaxed in her bed and added a sticker over one nipple to adhere to the Instagram guidelines.  Baring all: After walking in the Tommy Hilfiger show, Naomi Campbell stripped off the baggy set and posed topless from her bed for her 8.4 million fans on Sunday Naomi used one hand to take the photo and had her long brunette tresses covering up her other nipple.  Strategic placement: Naomi used one hand to take the photo and had her long brunette tresses covering up her other nipple Runway star: The UK beauty’s topless selfie comes after she walked the runway at the TommyNow show in London on Sunday The UK beauty’s topless selfie comes after she walked the runway at the TommyNow show in London on Sunday.  Can’t miss her! She stunned in a very baggy tracksuit set with highlighter yellow accents throughout It comes after she was recently presented with the Fashion Icon trophy during the star-studded British Fashion Awards. The model was in tears as she accepted the prize from Sir Jony Ive, before thanking her mother for ‘ra...

Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow

Transmission of Plasmodium parasites to the mosquito requires the formation and development of gametocytes. Studies in infected humans have shown that only the most mature forms of Plasmodium falciparum gametocytes are present in circulation, whereas immature forms accumulate in the hematopoietic environment of the bone marrow. We used the rodent model Plasmodium berghei to study gametocyte behavior through time under physiological conditions. Intravital microscopy demonstrated preferential homing of early gametocyte forms across the intact vascular barrier of the bone marrow and the spleen early during infection and subsequent development in the extravascular environment. During the acute phase of infection, we observed vascular leakage resulting in further parasite accumulation in this environment. Mature gametocytes showed high deformability and were found entering and exiting the intact vascular barrier. We suggest that extravascular gametocyte localization and mobility are essential for gametocytogenesis and transmission of Plasmodium to the mosquito. Transmission to mosquitoes is an essential part of the Plasmodium parasite’s life cycle and a target of current intervention...